Cp 13/516 B, C, Vellalasseri Nitc(Via), Poolacode, Kozhikode
  • For Appointment (+91) 495 2289500, 2289505, 7199525
  • For Emergency (+91) 495 2289531
  • Research


    We, at the MVR Cancer Centre & Research institute are bestowed with the widest range of patients in large numbers and recognized by Department of Scientific and Industrial research (DSIR) – Government of India in 2019. Department of Clinical research was commissioned in 2019 to temper the vast data generated from clinics and draw meaningful conclusions with clinical endpoints. The clinical research department offered a wide range of services from collection, maintenance, quality control & analysis of data to design & execution of prospective trials of importance to the institute and nation. The primary aim was to generate easily testable hypothesis from focused retrospective analysis and to test novel avenues with survival or quality of life end points in observational studies or randomized trials. Department of clinical research has 3 functional units

    List of Functional Units

    1. Clinical Trial Unit
    2. Institute Ethics Committee
    3. Research dissemination centre
    This department lead by (Senior research coordinator) and team.
    Team Members
    Ms Roshna Wilson (Clinical research associate)
    Ms Rakhi T S (Clinical research associate)
    Ms Panchami V (Clinical research coordinator)
    Ms Neethu K (Clinical research Coordinator)
    Mr Midhul P (Project assistant)

    1. Clinical Trial Unit

    An international centre for clinical trials has been established At MVR Cancer Centre & Research Institute Hospital not only to initiate clinicians in the concept of scientific and evidence-based medicine but also to address
    burning medical and epidemiological questions in which the west is unlikely to have any interest. Scientific leads from laboratory ultimately need to be answered in human subjects in the form of a randomized clinical
    trial. But, due to a lack of understanding as to how such a question should be addressed in a clinical setting and a lack of interaction between the clinician and the laboratory scientist, many important scientific
    leads are lost by default. The scientific community, other funding agencies and ultimately patients may benefit from testing the efficacy of newly synthesized biological products such as engineered enzymes, genetic
    materials and other substances emanating from laboratories. In the sphere of public health, where very large community initiatives are a norm, would benefit from having a centralized facility to conduct trials involving
    thousands of subjects. The randomized clinical trial offers a unique opportunity to test these issues scientifically before they are sanctioned for routine health care.

    List of ongoing clinical trials (recruitment phase)
    SL N Name of the clinical trial Sponsor
    1 A Phase 3, Randomized, Multi-center, Open-label Study of Trastuzumab Deruxtecan (T-DXd) Versus Investigator’s Choice Chemotherapy in HER2-low, Hormone Receptor Positive Breast Cancer Patients whose Disease
    has Progressed on Endocrine Therapy in the Metastatic Setting (DESTINY-Breast06)
    2 SERENA-4

    A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received
    Any Systemic Treatment for Advanced Disease

    3 RI-01-006

    Randomised, Double-Blind, Parallel-Group, Phase Iii Study To Compare The Efficacy, Safety, And Immunogenicity Of Proposed Rituximab Biosimilar (Drl_Ri) With Mabthera In Subjects With Previously Untreated, Stage Ii-Iv, Cd20+, Low Tumour Burden Follicular
    Lymphoma (RI-01-006-Flinter Study )

    Dr Reddy’s Laboratories
    4 A Multicenter, Randomised, Double blind, Parallel, Phase III Global Study to Assess the Efficacy and Safety of BP01 (Bevacizumab) when compared to Avastin®-EU In Combination with Carboplatin and Paclitaxel
    during Induction Phase and Bevacizumab Alone during the Maintenance Phase. In patients with Newly diagnosed or Recurrent Stage IIIB/IV Non-Squamous (ns) Non-Small Cell Lung Cancer (NSCLC).
    Axis Clinicals – Curatech Biologicals (Aurobindo Pharma)
    5 A single-arm, open-label Phase 4 study of darolutamide in addition to standard androgen deprivation therapy for Indian participants with high-risk non-metastatic castration-resistant prostate cancer (nmCRPC) Bayer Pharmaceuticals
    6 Phase III Study of Trastuzumab Deruxtecan (T-DXd) with or without Pertuzumab versus Taxane, Trastuzumab and Pertuzumab in HER2-positive, First-line Metastatic Breast Cancer (DESTINY-Breast09) . Astrazeneca
    7 A Phase Iii, Randomized, Open-Label Study Of Pralsetinib Versus Standard Of Care For First-Line Treatment Of Ret Fusion-Positive, Metastatic Non-Small Cell Lung Cancer Roche Products
    8 Randomized, Open Label, Multicenter, Phase Iii Study Of Entrectinib Versus Crizotinib In Patients With Locally-Advanced Or Metastatic Non-Small Cell Lung Cancer Harboring Ros1 Gene Rearrangements With And
    Without Central Nervous System Metastases”
    Roche Products
    9 A phase iii, randomized, double-blind, placebo controlled,
    multi-center, international study of durvalumab given
    concurrently with definitive chemoradiation therapy in patients
    with locally advanced, unresectable esophageal squamous cell
    carcinoma (KUNLUN)
    10 A phase iii, open-label, randomised study of datopotamab
    Deruxtecan (dato-dxd) in combination with durvalumab
    Compared with investigator’s choice of chemotherapy
    (paclitaxel, nab-paclitaxel or gemcitabine + carboplatin) in
    Combination with pembrolizumab in patients with pd-l1
    Positive locally recurrent inoperable or metastatic
    Triple-negative breast cancer (TROPION-BREAST05)
    11 A phase iii, randomised, open-label, multicentre, global study
    of datopotamab deruxtecan (dato-
    Dxd) in combination with durvalumab and carboplatin versus
    pembrolizumab in combination with platinum Based chemotherapy for the first-line treatment of patients with
    locally advanced or metastatic nsclc
    Without actionable genomic alterations (D926NC00001;

    2. Institute Ethics Committee

    The IEC is established to formalize and specify Institution’s commitment to the promotion of high scientific and ethical standards in patient care, professional education, clinical research, and community interests.

    Timely review and the safeguarding of high ethical standards formed the basis of the Institute Review board’s review process. These are essential for clinical research including student research, investigator initiated
    research and multi-centric multinational research. MVRCCRI ‘s Institutional Ethics Committee (MVRCCRI IEC) was established in August 2019. IEC regno is ECR/1259/INST/KL/2019. The Institutional Ethics Committees (IECs)
    are constituted by the Secretary, Care Foundation MVR Cancer Centre & Research Institute. IEC is essentially responsible for monitoring patient safety and assessing data during the course of the study in a manner that
    contributes to the scientific and ethical integrity of the study.

    SL N Name Designation Internalor External Organization Official Address E-mail Address Contact Number Letter Of Acceptance

    Paediatrics ,LLB, PGD in Medical Law and Ethics

    Chairperson External KMCT Medical College HOD Professor, Department of Paediatrics KMCT Medical College, Mukkam Rd, Manassery, Calicut drcherianpaed@yahoo.co.in 9847108965 Yes

    MD,DM Medical Oncology

    Member Secretary Internal MVRCCRI HOD & Senior Consultant, Medical Oncology MVR Cancer Centre and Research Institute, CP 13/516 B, C, Vellalasseri REC(via) Poolacode, Kerala-673601 drsreedharan@mvrccri.co 9496286696 Yes

    BA -LLB

    Legal Person External Self-Practice 1st floor, Zamorian Square,Rly Stn, Link Road,Calicut-673002 sun22244@yahoo.com 9349102503 Yes
    4 MS. SREEJA V. P


    Lay Person External HDFC Bank Cashier Karangattu Mana Farook P O Calicut 673632 sreejakarangat@gmail.com 9995102459 Yes


    Biomedical Scientist / Pharmacologist External KMCT Medical College KMCT Medical College,Mukkam Rd, Manassery, Calicut drubaidulla@gmail.com 7592948384 Yes
    6 FR. (DR) ANISH T

    PhD (Clinical Psychology)

    Social scientist / philosipher External Diocese of Thamarassery Bishop’s House,P B No: 1,Thamarassery P.O,Kozhikode aneeshtis@gmail.com 7045616525 Yes

    MD- General Medicine

    Clinician External KMCT Medical College Professor, General Medicine KMCT Medical College, Mukkam Rd, Manassery, Calicut dr.thulaseedharan@gmail.com 9847955875 Yes

    PhD Biotechnology –Life Science

    Basic medical scientist External Kannur University Director, Inter University Centre for Bioscience, Dept .Biotech and Microbiology, Kannur University Thalassery Campus,Palayad 670661,Kerala mharidasmm@gmail.com 9446252450 Yes

    MD, PhD, PGDMLE, FICP, FRCP (Edin)

    Clinician External Govt. Medical College Professor of Medicine & HOD of Emergency Medicine Department of General Medicine ,Govt Medical College,Kozhikode ,Kerala drchandni2022@gmail.com 9496286696 Yes

    MS, MCh Surgical Oncology

    Joint Member Secretary Clinician Internal 9446252450 MVRCCRI Senior Consultant, Department of Surgical Oncology MVR Cancer Centre and Research Institute, CP 13/516 B, C, Vellalasseri REC(via) Poolacode, Kerala 673601 drsyam@mvrccri.co 9447356010 Yes
    11 DR . LINEESH M C


    Biostatistician External NIT, Kozhikode NIT Campus P.O, Calicut Mukkam Road, Kattangal, Kozhikode, Kerala 673601 lineesh@nitc.ac.in 9495328642 Yes
    12 DR. SHAILAGE KURUP Clinician Internal MVRCCRI HOD & Senior Consultant, Department of Radiology MVR Cancer Centre and Research Institute, CP 13/516 B, C, Vellalasseri REC(via) Poolacode, Kerala 673601 drshailage@mvrccri.co Yes
    Contact IEC

    IEC administrator: Dr Uma V Sankar
    Clerical Staff: Ms Ashitha


    IEC office, Administration block
    MVR Cancer Centre & Research Institute
    Choolur, Vellalassery P O, Calicut, Kerala
    PIN: 673601
    Email id- iec@mvrccri.co

    3. Research dissemination center

    Research dissemination center involves the planning and implementation of the research protocols and communicating the research findings with wider audiences in way, that will facilitate research. It also conducting the
    workshops and training for the various topics.

    • Good Clinical Practice
    • Ethical principles and Helsinki Guidelines
    • Data management and Monitoring
    • Bio-Statistics and Bio-Informatics
    • Research Methodology.
    Ongoing & Completed research


    1 Knowledge attitude and practice of breast cancer screening among women in northern Kerala:
    2 Epidemiologic profile of diabetes among newly diagnosed cancer patients in a tertiary care setting
    3 Clinical Trail Phase III: Indication: low tumour burden follicular lymphoma
    4 Immunophenotypic profile of acute leukemia in a tertiary care centre in south India
    5 Assessment of tumor response and hormonal status in carcinoma breast post neoadjuvant therapy
    6 Deep learning technique for predecting organs at risk dose distribution of treatment plans in brain tumour patients
    7 Total neo-adjuvant treatment for high risk rectal adenocarcinoma
    8 Teravolt study
    9 Covacare- Development of Remote Patient Monitoring System : Use of Artificial Intelligence Technology
    10 Development of multiple linear regression model for parotid mean dose prediction in treatment planning
    11 IMCOC study-the impact of the COVID-19 pandemic on patients with cancer and the consequences for their treatment will be investigated.
    12 Kerala Triple Negative Breast Cancer Study
    13 A prospective study of clinical and microbiological characteristics of febrile neutropenia in solid and hematological malignancies
    14 Quality of life & lived experience of women after radical mastectomy- A study to assess the quality of life( QOL) & lived experience of women after radical mastectomy.
    15 Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) – a single centre ICU experience
    16 Development of multi-channel brachytherapy applicator
    17 A prospective study to assess the incidence of biopsy tract seeding in patients with osteosarcoma and Ewing’s sarcoma of the extremity
    18 Genomic profiling of high grade serous ovarian carcinoma to predict platinum sensitivity: pilot study
    19 Prognostic significance of Nutrition Risk Index in patients with carcinoma stomach and GE junction
    20 Total parietal peritonectomy at interval cytoreductive surgery with/without HIPEC for advanced (Stage III-C/IV-A) ovarian, fallopian tube and primary peritoneal cancer- A prospective comparative multi-institutional
    21 ERAS Practices- working Guidelines and compliance check list
    22 Patient preference for non-operative treatment strategy in locally Advanced Rectal Cancers; a cross-sectional survey
    23 Genome sequencing of multi drug resistant clinical isolates for antimicrobial resistance surveillance
    24 Clinicopathological profile of epithelial ovarian tumors in a tertiary cancer care centre in south india – a descriptive study.
    25 Automated tissue necrosis segmentation tool using h&e stained histopathological images
    26 Genetic profiling of carcinoma endometrium and prognostic significance of mutations in pole gene
    27 Patient preference for non-operative treatment strategy in locality advanced rectal cancers : a cross sectional survey
    28 An exploratory study on pain perception among cancer patients
    29 Indian covid-19 childhood cancer registry
    30 Clinical course, pathological spectrum and outcomes in paediatric rare tumors in india: a prospective observational study
    31 Resilience of care givers of pediatric cancer patients in kerala
    32 Assessment of nutritional status at diagnosis and over a 6 -months treatment period in paediatric oncology patients haematology malignancies and solid tumours
    33 India co-operative neuroblastoma study :non –high risk (icons –nhr18) study
    34 Glucorticoid induces bradycarisa in children undergoing induction chemotherapy in acute lymphoblastic leukemia
    35 The impact on covid-19 pandemic on the care of children with cancer in india
    36 Patterns of care and survival of wilms tumor in india – a retrospective multi-centric study
    37 A Prospective Collaborative Study for Newly Diagnosed Patients with Retinoblastoma in India (InPOG – RB – 19 – 01)
    38 Clinical audit of interval compressed VAC/IE schedule in children receiving chemotherapy for Ewing’s Sarcoma
    39 Comparison of different nutritional assessments in detecting malnutrition in post gastrectomy patients
    40 Prognostic significance of nutrition risk index in patients with carcinoma stomach and GE junction
    41 Assessment of Nutritional status at Diagnosis and over a 6 -months treatment period in pediatric oncology patients Hematology malignancies and solid Tumors.
    42 Analysis of biological variation, interfering substances and quality management in clinical biochemistry lab
    44 Evaluation of sensory changes in neck after selective neck dissection for primary oral cavity cancers
    45 Deep contour: a u-net based auto-contouring tool for delineration in head and neck based computed Tomography Images
    46 Clinicopathological characteristics of differentiated thyroid cancer
    47 Impact of radiation therapy on oral health quality in oral cancer patients
    48 Knowledge attitude and practice of breast cancer screening among women in Northern Kerala
    49 Factors affecting blood component expiry in a blood centre attached to an Oncology Centre
    50 Covid vaccination coverage among health care workers in a tertiary cancer care centre
    51 Covid test positivity rate and its clinical relevance among cancer patients in a tertiary cancer care center
    52 Genome sequencing of Multi Drug Resistant clinical isolates for antimicrobial resistance surveillance
    53 Microwave ablation of hepatocellular carcinoma: Outcomes and prognostic factors
    54 Radiogenomic role with respect to MRI techniques, 1p19q status and WHO grade II/III gliomas
    55 ARGOS Research Project: A study protocol for a federated multi-centre deep-learning neural network collaborative research project on lung cancer Gross Tumour Volume auto segmentation following the Personal Health Train method
    56 Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma Patients of Indian Ethnicity
    57 Validating Malnutrition Self Screening Tool
    58 Integrated Clinico-pathological and treatment outcome analysis of extra-cranial malignant germ cell tumors in children and adolescents in India. A Retrospective Multi-Centric Study
    59 Indian Childhood Acute Promyelocytic Leukemia Study
    60 Impact of NeoToX Precision Oncology System on Therapeutic Decision Making in 20 Patients with Relapse or Refractory Cancer
    61 Can Mammography Help in Predicting
    The molecular Subtype of Breast Cancer ?- A Retrospective Analysis
    62 Retrospective Assessment of PSMA PET CT and MRI in the Detection and staging of Prostate Cancer: A comparative analysis
    List Of Publications

    1. Ranjith C.P., Puzhakkal, N., Arunkrishnan, M. P., Vysakh, R., Irfad, M. P., Vijayagopal, K. S., & Jayashanker, S. (2021). Mean parotid dose prediction model using machine learning regression method for intensity-modulated
    radiotherapy in head and neck cancer. Medical dosimetry : official journal of the American Association of Medical Dosimetrists, 46(3), 283–288. https://doi.org/10.1016/j.meddos.2021.02.003.

    2. Francis, S., Jayaraj, P.B., Pournami, P.N. Manu Thomas, Ajay Thoomkuzhy Jose, Allen John Binu & Niyas Puzhakkal. ThoraxNet: a 3D U-Net based two-stage framework for OAR segmentation on thoracic CT images. Phys Eng Sci
    Med (2022). https://doi.org/10.1007/s13246-022-01101-x.

    3. Krishnan, M., Bhagyalakshmi, A. T., Holla, R., Puzakkal, N., Ranjith, C. P., Vysakh, R., Irfad, M. P., Ramasubramanian, V., Hu, J., & Momeen, M. U. (2021). A technique for quantifying the sensitivity of dosimetric tool
    gamma with 2D detector array in pretreatment IMRT plans by segment deletion method. La Radiologia medica, 126(3), 453–459. https://doi.org/10.1007/s11547-020-01259-y.

    4. R Vysakh, MM Musthafa, CV Midhun, P. Niyas, P T Anjana, MP Arun Krishnan, CP Ranjith, MP Irfad & R Ganapathi Ramanet. (2020). Experimental determination of thermal neutron fluence around Elekta Versa HD linear accelerator
    for various photon energies. Biomed. Phys. Eng. Express 6 055018. https://doi.org/10.1088/2057-1976/abac90.

    5. Niyas Puzhakkal, Abdullah KK, Dinesh Makuny, Arun Krishnan M.P, Ranjith C. Poyil, Vysakh R,.(2019). Validation of Dolphin dosimetry in three dimensional patient-specific quality assurance programme. Reports of Practical
    Oncology & Radiotherapy 24(5), 481-490. https://doi.org/10.1016/j.rpor.2019.07.006.

    6. Niyas, Puzhakkal., Abdullah, K., Noufal, M., & Vysakh, R. (2019). Quality assurance of linear accelerator:A comprehensive system using electronic portal imaging device. Journal of Radiotherapy in Practice, 18(2), 138-149.

    7. Niyas Puzhakkal, Ranjith, C.P., Arun, M.P., Vysakh, R., Abdullah, K.K., & Noufal, M.P. (2018). Evaluation of structural shielding adequacy of a medical linear accelerator. (2018) India: Raja Ramanna Centre for Advanced
    Technology. http://inis.iaea.org/search/search.aspx?orig_q=RN:49082890.

    8. Bene A. Ekine-Afolabi, 1 , 2 , * Anoka A. Njan, Solomon O. Rotimi, Anu R. I., Attia M. Elbehi, , Elizabeth Cash, and Ademola Adeyeye, The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles,
    and Gut Microbiome-Virome in Colorectal Cancer Initiation and Progression, Front Oncol. 2020; 10: 583372. Published online 2020 Dec 14. doi: 10.3389/fonc.2020.583372

    9. Sudeep Guptha, Shona Nag, Shyam Aggarwal, Amit Rauthan, and Narayanankutty Warrier Maintenance therapy for recurrent epithelial ovarian cancer: current therapies and future perspectives – a review, J Ovarian Res. 2019;
    12: 103.Published online 2019 Nov 4. doi: 10.1186/s13048-019-0579-0

    10. Narayanankutty Warrier, Uma V Sankar, Sreedharan P S, Nirmal V, Sajeevan K V, Ajmal Sherif, Detect Early Be Safe–Care for Mother (DEBS-CaM) project: School-based interventions to improve awareness and screening for
    breast cancer among the young mothers of Kerala. 10.1200/JCO.2020.38.15_suppl.e13570 Journal of Clinical Oncology 38, no. 15_suppl

    11. Bhatt, A., Sinukumar, S., Rajan, F., Damodaran, D., Ray, M., Zaveri, S., Kammar, P., & Mehta, S. (2019). Impact of Radicality Versus Timing of Surgery in Patients with Advanced Ovarian Cancer (Stage III C) Undergoing
    CRS and HIPEC-a Retrospective Study by INDEPSO. Indian journal of surgical oncology, 10(Suppl 1), 57–64. https://doi.org/10.1007/s13193-019-00875-z

    12. Damodaran D, Naidu BK, Varghese JC, et al. A Prospective Study on Level of Concordance Between Core Needle Biopsy and Surgical Specimen for Assessing Oestrogen Receptor, Progesterone Receptor, and Her2/Neu Receptor
    Status in Carcinoma Breast and Its Implications on Treatment Decisions. Indian J Surg Oncol. 2020;11(3):446-450. doi:10.1007/s13193-020-01146-y

    13. Bhatt, A., Kammar, P., Mehta, S., Damodaran, D., Zaveri, S., Patel, M. D., Sinukumar, S., Ray, M., & Seshadri, R. (2019). Chasing Rainbows? the Possibility of “Cure” in Patients with Colorectal Peritoneal Metastases
    Undergoing Cytoreductive Surgery and HIPEC-a Retrospective Study by INDEPSO. Indian journal of surgical oncology, 10(Suppl 1), 49–56. https://doi.org/10.1007/s13193-019-00879-9

    14. Patel, M. D., Damodaran, D., Rangole, A., Shaikh, S., Shah, K., Bagwade, R., & Bhatt, A. (2019). Hyperthermic Intrathoracic Chemotherapy (HITHOC) for Pleural Malignancies-Experience from Indian Centers. Indian journal
    of surgical oncology, 10(Suppl 1), 91–98. https://doi.org/10.1007/s13193-018-0859-y

    15. Afra TP, Nair PP, Thanseer NTK, Razmi TM. Crizotinib-Induced Severe Photosensitive Dermatitis in a Carcinoma Lung Patient. Indian Dermatol Online J. 2020;12(1):188-189. Published 2020 Sep 28. doi:10.4103/idoj.IDOJ_291_20

    16. Periasamy K, Karunanithi G, Cholayil S, Dharanipragada K, Neelakanadan V. Dosimetric comparison between interstitial brachytherapy and volumetric-modulated arc therapy for tumor bed boost in breast cancer. J Contemp
    Brachytherapy. 2021;13(3):302-309. doi:10.5114/jcb.2021.106141

    17. Narayanankutty Edavalath Warrier, Uma V Sankar, Sreedharan P. S., Prasanth V. Parameswaran, Sajeevan K. V., Nirmal V. Can COV Direct: Effectiveness of a tele-medicine self- care interventions for cancer survivors during
    COVID 19 pandemic.J Clin Oncol 39, 2021 (suppl 15; abstr 1583). DOI. 10.1200/JCO.2021.39.15_suppl.1583

    18. Radhakrishnan C, Sankar UV, Rajendran VR, et al. Psychosocial impacts of quarantine among survivors of the Nipah virus infection: a qualitative study. Journal of Global Health Reports. 2021;5:e2021092. doi:10.29392/001c.28993

    19. Yamini Krishnan, Gazel Sainulabdin, V. Sankar Uma, P.S. Sreedharan, Narayanankutty Warrier. Clinical audit of a Paediatric Emergency Warning Score (PEWS) in the paediatric oncology unit of a newly established tertiary
    cancer institute, Pediatric Hematology Oncology Journal,Volume 5, Issue 3,2020,Pages 69-74,ISSN 2468-1245, https://doi.org/10.1016/j.phoj.2020.06.006.

    20. Warrier, Narayanankutty Edavalath, Uma V. Sankar, Sreedharan P S, and Ajmal Sherif. “Triple-negative and non–triple-negative breast cancer in a south Indian cohort.” Journal of Clinical Oncology 38, 15_suppl (May 2020):
    e13110-e13110. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e13110.

    21. Krishnan, Y., Gazel, S., Sankar, U. V., & Sreedharan, P. S. (2021). Glucocorticosteroid Induced Bradycardia in Children Receiving Induction Chemotherapy for Acute Lymphoblastic Leukaemia-an Unrecognised Phenomenon.
    Asian Oncology Research Journal, 4(1), 14-23.Retrieved from.https://www.journalaorj.com/index.php/AORJ/article/view/30129

    22. Anu R I, Aastha Vatsyayan, Ambily Sivadas, Dileep Damodaran, Kurt Van der Speeten. Multi-omic analysis classifies colorectal cancer into distinct angiogenic and immunogenic subtypes based on anatomical laterality. Cancer
    Research. 2022. Abstract published by AACR.

    23. Anu R I et al. Mutational Signatures, Variant Topography, and Signaling Pathways in Breast Cancer: A futuristic approach to personalized care. Translational Genomics. 2020. doi:10.9777/tg.2020.10001

    24. Anu R I, Gauri Mittal, Aastha Vatsyayan, Kavita Pandhare, Vinod Scaria. MUSTARD—a comprehensive resource of mutation-specific therapies in cancer, Database, Volume 2021,https://doi.org/10.1093/database/baab0423.

    25. Cash, E., Sephton, S., Woolley, C., Elbehi AM, Anu R I, Ekine-Afolabi B, Victor Kok. The role of the circadian clock in cancer hallmark acquisition and immune-based cancer therapeutics. J Exp Clin Cancer Res 40, 119
    (2021). https://doi.org/10.1186/s13046-021-01919-5

    26. Elbehi AM, Anu R I, Ekine-Afolabi B, Cash E. Emerging role of immune checkpoint inhibitors and predictive biomarkers in head and neck cancers. OralOncol.2020;109:104977. doi.org/10.1016/j.oraloncology.2020.104977

    27. Ekine-Afolabi BA, Njan AA, Rotimi SO, R I Anu, Elbehi AM, Cash E, Adeyeye A. The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles, and Gut Microbiome-Virome in Colorectal Cancer Initiation
    and Progression. Front Oncol. 2020 Dec 14;10:583372. doi: 10.3389/fonc.2020.583372.

    28. The GUaRDIAN Consortium, Vinod Scaria, Sridhar Sivasubbu. Genomics of Rare Genetic diseases-experinces from India. Human Genomics. 2019;13(53).

    29. Anu R I, Kaur C, Bhavsar P, Prasad J. Genotyping of Lipoprotein(a) Gene Variants in Coronary Artery Disease in Indian Population. Indian J Med Biochem 2021; 25 (2):76-82. doi:10.5005/jp-journals-10054-0178

    30. Sudheesh Manoharan, Haripriya Chari, Santhoshkumar.N. Distribution of Metastatic Lymph Nodes in Primary Oral Squamous Cell Carcinoma Journal of Head & Neck Physicians and Surgeons ¦ October 2019 ¦ Volume 7 ¦ Supplement

    31. Krishnan Y, Smitha B ,Cholayil S .Paroxysmal Sympathetic Hyperactivity – An under recognised entity in paediatric brain tumours: Case report and Review of literature Indian J Med Paediatr Oncol 2020;41:254-6

    32. Krishnan Y, Smitha B , Sreedharan PS .Consumption Coagulopathy in Paediatric Sol- id Tumours- A retrospective analysis and review of literature Gulf J Oncolog. 2019 Sep ; 31:66-71

    33. Yamini K, Gazel S, V. Uma VS, Sreedharan PS, Narayanankutty W. Clinical audit of a Paediatric Emergency Warning Score (PEWS) in the paediatric oncology unit of a newly established tertiary cancer institute. Pediatric
    Hematology Oncology Journal. 2020 Sep ; 5 (3) : 69-74

    34. Krishnan, Y., Gazel, S., Sankar, U. V., & Sreedharan, P. S. (2021). Glucocorticos- teroid Induced Bradycardia in Children Receiving Induction Chemotherapy for Acute Lymphoblastic Leukaemia-an Unrecognised Phenomenon.
    Asian Oncology Research Journal. 2021; 4(1), 14-23.

    35. Yamini K, Gazel S. Shailaj SK, VP Muralikrishnan .Multiple infectious intracranial aneurysms in a child with acute lymphoblastic leukaemia – a fatal complication in a highly curable disease. Asian Hematology Research
    Journal. 2021; 4(2),11-17.

    36. Totadri S , Mahajan A, Gupta V , Das A, Meena JP, Singh M , Mohammed S , Ag- garwal P, Tuladhar S, Seth R, Naseem S, Varma N, Trehan A, Bansal D -Treatment and outcome of chronic myeloid leukemia in children and adolescents
    : The Indian Pediatric Oncology Group – CML-16-01 Multicentric Study. Poster presented at The 24th European Hematology Association Congress (EHA) 2019 ; June 13 -16, Ams- terdam

    37. Sharma J, Mahajan A, Bakhshi S, Patil V, Verma N, Radhakrishnan V, Singh A, Kayal S, Seth R, Pushpam D, Arora RS. The impact of COVID-19 pandemic on access to treatment for children with cancer in India and treating
    center practices. Cancer. 2021 Oct 7. doi: 10.1002/cncr.33945. Epub ahead of print..

    Oral presentation

    1. Vishnu K S ,Dileep Damodaran. Enhanced Recovery after surgery (ERAS) in patients undergoing cytoreductive surgery (CRS)& Hyperthermic Intraperitoneal Chemotherapy (HIPEC) – Complaince and Outcome experience at a tertiary
    care centre. MIDCON IASO 2022

    2. Uma V Sankar, Yamini Krishnan, Rakhi T S, Roshnawilson, Gazel S, Public awareness about Childhood Cancer”.14th SIOP Asia Conference, China

    Poster Presentations
    • Anu RI, Dileep Damodaran, MultiOmics analysis classifies colorectal cancer into distinct angiogenic and immunogenic subtypes based on anatomical laterality, American Association for Cancer research Annual meeting 2022,
      New Oreland
    • Narayanankutty Edavalath Warrier, Uma V Sankar, Sreedharan P S, Prasanth V Parameswaran, Sajeevan K V, Nirmal V CanCovDirect: Effectiveness of a Tele-Medicine Self-Care Intervention for Cancer Survivors during Covid
      19 Pandemic. ASCO annual meeting 2021
    • Krishnan Y, Smitha B ,Cholayil S. Paroxysmal Sympathetic Hyperactivity-An under- recognised entity in Paediatric Brain tumours: Case report and Review of literature. Poster presented at International Oncology conference,
      MVR Cancer Centre and Re- search Institute, 2018;Sep 28-30; Calicut
    • Krishnan Y, Smitha B.Consumption Coagulopathy in Paediatric Solid Tumours- A retrospective analysis from a tertiary referral cancer centre. Poster presented at In- ternational Oncology conference, MVR Cancer Centre
      and Research Institute, 2018;Sep 28-30; Calicut
    • Sankar U, Krishnan Y, Warrier NK. Paediatric Langerhans cell histiocytosis: single institution experience over 2 years.Poster presented at 2nd International Oncology conference, MVR Cancer Centre and Research Institute,
      2019 ; Aug 30-Sep1 ; Cali- cut
    • Sankar U, Krishnan Y, Warrier NK. Public perception about childhood cancers: A mixed method study .Poster presented at 2nd International Oncology conference, MVR Cancer Centre and Research Institute, 2019 ; Aug 30-Sep1
      ; Calicut
    • Krishnan Y, Gazel S ,Sankar U, Warrier NK. Clinical Audit of a Paediatric Emer- gency warning score (PEWS) in the paediatric oncology unit of a newly established tertiary cancer institute: Poster at 10 th annual Conference
      of Hematology Oncology. Chapter , IAP , Kerala 2019 ; Oct 6 ; Thalassery
    • Santhosh kumar N , Krishnan Y, Smitha B, Warrier NK, Manamel M. Fungal suppu- rative Thyroiditis in a child with acute lymphoblastic leukemia. Poster presented at 19th national conference of Foundation for head and
      neck oncology FHNO 2019; Oct 11-13 ;Chennai
    • Krishnan Y, Sankar U, Gazel S ,Warrier NK. What happens to the parent when their child gets diagnosed with cancer ? A common man’s perspective – a qualitative study. Poster presented at XIIth SIOP Asia Congress 2021,
      Mar 19-21; Mumbai
    • Sankar U, Krishnan Y, Gazel S ,Warrier NK. Parents perception of childhood cancers in the Malabar Region schools of kerala : A mixed method study. Poster presented at XIIth SIOP Asia Congress 2021, Mar 19-21; Mumbai
    • Yamini Krishnan, KrishnanVP, Gazel S, Somdipa Pal, Vyshna Somnath ,Liya Vargh- ese ,Sandhya CT. Factors predicting resilience in parents of paediatric cancer patients in Kerala. Poster presented at 24 th Annual Pediatric
      Hematology Oncology Confer- ence 2021, Dec 10-12: Hyderabad
    • Somdipa Pal, Yamini Krishnan, Gazel S, KrishnanVP. Extrapleural Pneumonectomy as a surgical management in achild with primary pleural synovial sarcoma-a case report. Poster presented at 24 th Annual Pediatric Hematology
      Oncology Conference 2021, Dec 10-12: Hyderabad
    • Somdipa Pal, Yamini Krishnan, KrishnanVP, Gazel S. Transitioning of ifosfamide based chemotherapy from the inpatient to an outpatient setting-A cost effective and safe option. Poster presented at 24 th Annual Pediatric
      Hematology Oncology Con- ference 2021, Dec 10-12: Hyderabad
    Research Collaborations
    • Memorandum of understanding (MOU) between National Institute of Technology, Calicut (NIT) for various projects
    • MOU with University of Massricht, Netherlands
    • MOU with and Arya Vaidya Sala Kottakal (AVS Kottakal) in the project titled ‘Setting up Centre of Excellence in Cancer Research’ to Ministry of AYUSH Government of India
    • MOU with Department of Obstetrics, Government Medical College, Calicut
    • MOU with CSIR – Institute of Genomics and integrative biology, Delhi in collaborative research
    • MOU with KMCT Dental College
    • MOU with Malabar Medical College
    • MOU with Travencore Analytics
    • MOU with Comtrust hospitals
    Internship/ trainee opportunities

    Department of clinical research offers internship opportunities in clinical trial unit for various streams of students ex: Pharm D Students , B Pharm and Msc Biotech students.


    The Visionary

    Respectfully called MVR, the late MV Raghavan was one of the revolutionary leaders of the Communist movement in Kerala. Born in an ordinary family in Pappinissery, Kannur, his political life began in his early teens. He served two terms as Minister of Co-operation and Ports in Kerala during 1991-1996 and 2001-2006. MVR revolutionized the co-operative sector by taking the people-powered movement to healthcare and education in the State. MV Raghavan realized the role of the co-operative movement in social development and job creation and he was instrumental in setting up various institutions in the state.